3,5-Dichloro-2-cyanopyridine CAS#85331-33-5
3,5‑Dichloro‑2‑cyanopyridine is a vital fine‑chemical intermediate widely applied as industrial raw material for pharmaceuticals, agrochemical pesticides and feed‑related synthesis. It can be utilized for manufacturing vitamin‑B series products, insecticides and cardiotonic agents.
It serves as a key intermediate for the industrial production of nicotinic acid and nicotinamide. Besides, it is adopted in the synthesis of pharmaceuticals, pesticides and rubber additives.
In agrochemical industry, it is mainly used for preparing paddy‑field herbicide Guacaodan, which possesses promising market development prospects.
In pharmaceutical field, it is applied to synthesize multiple APIs: Roxatidine acetate hydrochloride for digestive disorders, ethyl acetylaminobenzoate for neurological treatment, and histamine‑receptor blocker sustained‑release preparations such as roxatidine acetate hydrochloride.
3,5-Dichloro-2-cyanopyridine Chemical Properties
| Melting point | 101-103°C |
| Boiling point | 271.9±35.0 °C(Predicted) |
| density | 1.49±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | -4.61±0.10(Predicted) |
| color | White to Light yellow |
| BRN | 4390101 |
| InChI | InChI=1S/C6H2Cl2N2/c7-4-1-5(8)6(2-9)10-3-4/h1,3H |
| InChIKey | ATUOLSDAAPMVJJ-UHFFFAOYSA-N |
| SMILES | C1(C#N)=NC=C(Cl)C=C1Cl |
| CAS DataBase Reference | 85331-33-5(CAS DataBase Reference) |
