Diethylene Glycol Ethyl Ether CAS#111-90-0

  1. Low Volatility & Controlled Slow Evaporation: High boiling point ~196–202°C and low vapor pressure. Extends open time / wet-edge time for coatings & inks; prevents premature drying, skinning and nozzle clogging, delivers smooth film leveling and uniform gloss.

  2. Mild Odor & Good Formulation Compatibility: Light, non-irritating odor. Compatible with latex, acrylic, PU, nitrocellulose and many polymer systems, widely accepted in coatings, printing ink, cleaning, cosmetic and pharma topical formulas.

  3. High Chemical Stability & Inertness: Stable under normal storage and processing conditions; low reactivity, helps maintain long shelf life of finished formulations. Works reliably as a coupling agent, coalescing agent and processing aid.

  4. Effective Penetration & Solubilization Booster: Well-known as a penetration enhancer for personal care and topical pharmaceutical products, improves solubility and skin delivery of lipophilic active ingredients.

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Products Description

Diethylene glycol monoethyl ether is a colorless, stable, hygroscopic liquid with a mild and pleasant odor. It is fully miscible with water, alcohols, ethers, ketones, aromatic and aliphatic hydrocarbons, as well as halogenated hydrocarbons. Due to the presence of ether, alcohol, and hydrocarbon groups in its molecular structure, it exhibits excellent solvent properties and can dissolve a wide range of substances, including oils, fats, waxes, dyes, camphor, and natural resins such as copal, kauri, mastic, rosin, sandarac, and shellac, along with various synthetic resins. It is commonly employed as a solvent in synthetic resin coating formulations and lacquers, particularly in applications requiring high-boiling-point solvents.

 

Chemical Properties

Melting point 

-80 °C

Boiling point 

202 °C(lit.)

density 

0.999 g/mL at 25 °C(lit.)

vapor density 

4.63 (vs air)

vapor pressure 

0.12 mm Hg ( 20 °C)

refractive index 

n20/D 1.427(lit.)

Fp 

205 °F

storage temp. 

Store below +30°C.

solubility 

water: soluble

form 

Liquid

pka

14.37±0.10(Predicted)

color 

Clear colorless

Odor

Weakly fruity; mild and characteristic.

biological source

synthetic

explosive limit

1.8-12.2%(V)

Water Solubility 

Miscible

Thermal Conductivity

0.188 W/(m·K) at 50 ℃

Sensitive 

Hygroscopic

Merck 

14,1800

BRN 

1736441

Henry's Law Constant

4.4×102 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)

Stability:

Stable. Combustible. Note wide explosion limits. Incompatible with strong oxidizing agents, strong acids, acid chlorides, acid anhydrides. Hygroscopic.

Cosmetics Ingredients Functions

HUMECTANT
PERFUMING
SOLVENT

Cosmetic Ingredient Review (CIR)

Diethylene Glycol Monoethyl Ether (111-90-0)

InChI

1S/C6H14O3/c1-2-8-5-6-9-4-3-7/h7H,2-6H2,1H3

InChIKey

XXJWXESWEXIICW-UHFFFAOYSA-N

SMILES

CCOCCOCCO

LogP

-0.54 at 20℃

CAS DataBase Reference

111-90-0(CAS DataBase Reference)

NIST Chemistry Reference

Ethanol, 2-(2-ethoxyethoxy)-(111-90-0)

EPA Substance Registry System

Diethylene glycol monoethyl ether (111-90-0)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

36-20-36/37/38

Safety Statements 

23-24/25-39-26-36

WGK Germany 

1

RTECS 

KK8750000

Autoignition Temperature

204 °C

TSCA 

TSCA listed

HS Code 

29094400

Storage Class

10 - Combustible liquids

Hazardous Substances Data

111-90-0(Hazardous Substances Data)

Toxicity

LD50 orally in rats: 8.69 g/kg (Smyth, Carpenter)

Product Applications

Diethylene glycol monoethyl ether has a low freezing point and low viscosity at low temperatures, making it suitable for use in brake fluid formulations. In the paint industry, it serves as a flow and gloss enhancer. It is also utilized in the manufacture of printing inks and as a cleaning agent in offset printing. In the textile industry, it acts as a solvent for dyestuffs during the printing and dyeing of fibers and fabrics. Additionally, it is used in the production of wood preservatives.

 

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