Products Description
4-AminobutyricAcid(GABA)isanimportantbiochemicalcompoundwidelyusedinpharmaceuticalresearch,biochemicalstudies,andorganicsynthesis.Astheprimaryinhibitoryneurotransmitterinthecentralnervoussystem,itplaysakeyroleinregulatingneuronalactivitybyactivatingGABAreceptors(GABA-AandGABA-B)andmodulatingchlorideionconductivity.Itisinvolvedinvariousphysiologicalprocesses,includingneuralsignalregulationandbrainmetabolism.
Inpharmaceuticalapplications,GABAhasbeenusedinpreparationsrelatedtocerebrovasculardisordersandcertainneurologicalconditions.Itisalsostudiedforitspotentialroleinreducingbloodammonialevelsandsupportingthemanagementofhepaticencephalopathy.Additionally,itservesasanimportantpharmaceuticalintermediateandbiochemicalreagent,withapplicationsinmedicinalchemistry,neuroscienceresearch,andthedevelopmentofrelatedpharmaceuticalproducts.
Names and Identifiers
| Name | 4-Aminobutyric acid |
| CAS | No.56-12-2 |
| CID | 119 |
| EINECS(EC#) | 200-258-6 |
| Molecular Formula | C4H9NO2 (isomer) |
| Inchi | InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) |
| InChIkey | BTCSSZJGUNDROE-UHFFFAOYSA-N |
| Canonical Smiles | C(CC(=O)O)CN |
| Isomers Smiles | C(CC(=O)O)CN |
Properties
| Density | 1.2300 (estimate) |
| Melting point | 195?°C (dec.)(lit.) |
| Boiling point | 248oC at 760 mmHg |
| Refractive index | 1.4650 (estimate) |
| Flash Point | 103.8oC |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Precise Quality | 103.06300 |
| PSA | 63.32000 |
| logP | 0.51020 |
| Solubility | H2O: 1?M at?20?°C, clear, colorless |
| Appearance | H2O: 1?M at?20?°C, clear, colorless |
| Storage | Ambient temperatures. |
| Chemical Properties | White, powdery solid; savory, meat-like aroma |
| Color/Form | White to almost white |
| PKa | 4.031(at 25℃) |
| Water Solubility | H2O: 1?M at?20?°C, clear, colorless | SOLUBLE |
| Stability | Stable under normal temperatures and pressures. |
| StorageTemp | Store at RT. |
Product Application
4-Aminobutyric Acid (GABA) is an important pharmaceutical intermediate and biochemical compound widely used in pharmaceutical development, biochemical research, and organic synthesis. It has been studied for its potential effects on lipid metabolism, ammonia regulation, and brain metabolic activity. Historically, it has been used in certain pharmaceutical preparations associated with hepatic encephalopathy and cerebrovascular conditions. It has also been investigated in relation to neurological disorders, including cerebral hemorrhage, stroke-related complications, head trauma, uremia, and gas poisoning.
As the principal inhibitory neurotransmitter in the central nervous system, GABA plays a crucial role in regulating neuronal excitability and maintaining the balance of neural activity. It acts on GABA-A and GABA-B receptors, contributing to the regulation of chloride ion conductivity and neuronal signaling. Due to its important physiological functions, GABA is widely applied in neuroscience, biochemical studies, pharmaceutical research, and the development of related medicinal compounds.
