Pagoclone

1.GABA Receptor Modulating Activity: Pagolone acts as a specific GABA (Gamma-aminobutyric acid) receptor modulator, helping regulate GABAergic activity.

2.Potential Stuttering Reduction Effect: Pagolone has been shown to help reduce stuttering by influencing GABA (A) receptor function.

3.Novel Cyclopyrrolone Structure: As a novel cyclopyrrolone compound, Pagolone offers unique pharmacological properties compared with traditional GABA-related agents.

4.Partial GABA (A) Receptor Agonist: Pagolone functions as a partial agonist of GABA (A) receptors, providing targeted modulation of inhibitory neurotransmission.

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Product Description

Pagoclone is a selective modulator of GABA (Gamma-aminobutyric acid) receptors that has demonstrated the potential to reduce stuttering. It is a novel cyclopyrrolone compound that functions as a partial agonist of the GABA(A) receptor, contributing to its unique pharmacological profile.

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Pagoclone

Chemical Properties

Boiling point 582.1±50.0 °C(Predicted)
density 1.273±0.06 g/cm3(Predicted)
pka1.62±0.30(Predicted)
InChIInChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3
InChIKeyHIUPRQPBWVEQJJ-UHFFFAOYSA-N
SMILESC1(=O)C2=C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1=CC=C2C(=N1)N=C(Cl)C=C2
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Pagoclone

Product Application

Pagoclone is a selective GABA (gamma-aminobutyric acid) receptor modulator with the potential to alleviate stuttering. It is a novel cyclopyrrolone compound that functions as a partial agonist of the GABA(A) receptor.

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Pagoclone

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