Products Description
Magnesium aluminum silicate is widely used in pharmaceutical manufacturing as a multifunctional excipient, serving as an adsorbent, stabilizer, suspending agent, disintegrant for tablets and capsules, tablet binder, and thickener. Pharmaceutical excipients—also known as pharmaceutical auxiliaries—are chemical substances used in the pharmaceutical process that are distinct from the drug components themselves. As the generally inactive ingredients of pharmaceutical preparations, excipients play a key role in enhancing the stability, solubility, and processability of drug formulations. Moreover, they can influence the absorption, distribution, metabolism, and elimination (ADME) of combined medications, making them a critical consideration in drug development.
Chemical Properties
Field | Value |
|---|---|
English Name | Aluminium Magnesium Silicate |
English Synonyms | Magnesium Aluminum Silicate; Aluminium magnesium silicate (2:1:2); Silicic acid (H₄SiO₄), aluminum magnesium salt (2:1:2); Silanediolate, 1-oxo-, aluminum magnesium salt |
CAS Number | 12511-31-8 |
Molecular Formula | Al₂MgO₈Si₂ |
Molecular Weight | 262.43 g/mol |
EINECS Number | 235-682-0 |
Solubility | Practically insoluble in water and in organic solvents |
InChI | InChI=1S/Al.Mg.H4O4Si.5H/c;1-5(2,3)4;/h;1-4H; |
InChIKey | KFTMCVZESOVHAX-UHFFFAOYSA-N |
SMILES | [O-]Si([O-])[O-].[Mg+2].[Al+3] |
Product Applications
1. Pharmaceuticals
Suspending agent and stabilizer in oral suspensions, antacid formulations, and topical preparations.
Binder/disintegrant in tablet manufacturing.
Adsorbent and carrier for active pharmaceutical ingredients (APIs).
2. Cosmetics & Personal Care
Thickener, suspending agent, and stabilizer in toothpaste, creams, lotions, gels, and emulsions.
Improves texture, spreadability, and shelf stability of finished products.
3. Food
Anti-caking agent and stabilizer in powdered and processed food products (food-grade).
4. Industrial Applications
Coatings & paints: viscosity modifier and anti-settling agent.
Ceramics: binder and plasticity enhancer.
Pesticides: suspending agent for suspension concentrates (SC).
Polishing agents & lubricants: abrasive suspension and rheology control.
Lithium batteries: auxiliary material for slurry stability.
Engineering plastics: filler/processing aid.
