Products Description of Ambroxane CAS#6790-58-5
Ambroxan is one of the key aromatic constituents identified within ambergris tinctures derived from natural ambergris. It delivers a rich, powerful ambergris‑type aroma with delicate woody undertones. Boasting outstanding fixative performance, Ambroxan is extensively applied in perfumery. It reproduces the characteristic ambergris scent and serves as a sustainable substitute for natural ambergris.
Natural ambergris is a whale metabolic excretion occasionally collected along shorelines. It has been phased‑out from modern perfume manufacturing due to ethical concerns. First discovered in 1949, Ambroxan has grown into an indispensable raw material for fragrance creation. Within perfumery terminology, the “ambergris note” can also refer to amber‑styled fragrances formulated with cistus essential oil and cistus absolute as base components.
As a core building‑block for constructing ambergris‑style fragrance accords, Ambroxan ranks among the most widely‑adopted biodegradable ambergris‑type aroma molecules across the global perfume industry.

Ambroxane Chemical Properties
| Melting point | 74-76 °C (lit.) |
| alpha | -30 º (c=1% in toluene) |
| Boiling point | 273.9±8.0 °C(Predicted) |
| density | 0.939 |
| vapor pressure | 0.066Pa at 25℃ |
| FEMA | 3471 | 1,5,5,9-TETRAMETHYL-13-OXATRICYCLO(8.3.0.0(4,9))TRIDECANE |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystaline |
| color | White to Almost white |
| Odor | at 1.00 % in dipropylene glycol. ambergris old paper sweet labdanum dry |
| Odor Type | amber |
| optical activity | [α]20/D 29°, c = 1 in toluene |
| Water Solubility | 1.88mg/L at 20℃ |
| JECFA Number | 1240 |
| InChIKey | YPZUZOLGGMJZJO-LQKXBSAESA-N |
| LogP | 5.09 at 25℃ |
| CAS DataBase Reference | 6790-58-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 8 «alpha»,12-epoxy-13,14,15,16-tertanorlabdane(6790-58-5) |
| EPA Substance Registry System | Naphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)- (6790-58-5) |
Product Application of Ambroxane CAS#6790-58-5
Ambroxane delivers a unique, abundant ambergris scent, which makes it a premium raw material for luxury perfumes and cosmetic formulations. It features low skin irritation risk and shows no allergic response in animal studies, rendering it safe for fragrancing skin care, hair care and fabric products. It is widely adopted as an aroma ingredient and powerful fixative in soaps, talcum powders, creams and shampoos, with a normal use level ranging from 0.1% to 0.2%.
Freshly distilled pure Ambroxane carries a comparatively faint odor. Once diluted to 10% in ethanol and aged with air exposure, its aroma evolves into a softer, smoother and well‑balanced amber note. Thanks to its outstanding fixative capacity, it greatly boosts fragrance diffusion and substantivity, harmonizing the whole perfume accord from top notes down to base notes.
Within the tobacco sector, ambergris‑type flavorings are critical for building spiced tobacco aroma, and Ambroxane stands out as an outstanding option. It enriches the smoke flavor of blended cigarettes and is also popularly applied for flue‑cured tobacco and fine fragrance creation.
When used as a tobacco flavor modifier, Ambroxane blends naturally with inherent tobacco notes and masks unpleasant off‑odors and impurity smells. Only trace dosages are required to lift the overall sensory quality of tobacco. It works exceptionally well for blended cigarettes and helps highlight the characteristic flavor of Oriental tobacco.