2-Chloro-3-Methylpyrazine CAS#95-58-9

1.Versatile Intermediate for Chemical Synthesis: 2-Chloro-3-methylpyrazine is an important synthetic building block used in the preparation of a variety of pharmaceutical and medicinal compounds.

2.Reactive Chlorine Substituent: Its molecular structure contains a reactive chlorine group that can undergo substitution reactions, providing flexibility for further chemical functionalization and molecular modification.

3.Application in Pharmaceutical Development: This compound is utilized as a synthetic intermediate in the preparation of macrocyclic urea-based kinase inhibitors, supporting the development of potential therapeutic agents.

4.Valuable for Medicinal Chemistry Research: 2-Chloro-3-methylpyrazine offers useful applications in pharmaceutical research, drug discovery, and the development of novel bioactive compounds.

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2-Chloro-3-Methylpyrazine CAS#95-58-9 Product Description

2-Chloro-3-methylpyrazine is a halogenated pyrazine derivative that serves as a versatile building block in organic and pharmaceutical synthesis. The chlorine substituent attached to the pyrazine ring provides a reactive site for further chemical modification and substitution reactions, enabling the preparation of a variety of structurally diverse medicinal compounds. It is particularly valuable as a pharmaceutical intermediate in the synthesis of macrocyclic urea-based kinase inhibitors, making it useful in medicinal chemistry research, drug discovery, and the development of novel bioactive molecules.

2-Chloro-3-Methylpyrazine

2-Chloro-3-Methylpyrazine CAS#95-58-9 Chemical Properties

Boiling point 80 °C(Press: 27 Torr)
Density 1.234g/ml
Storage tempunder inert gas (nitrogen or Argon) at 2-8°C
Pka-0.31±0.10(Predicted)
Form Liquid
Color Colorless
LogP1.058 (est)
CAS DataBase Reference95-58-9(CAS DataBase Reference)
EPA Substance Registry SystemPyrazine, 2-chloro-3-methyl- (95-58-9)

2-Chloro-3-Methylpyrazine CAS#95-58-9 Safety Information

Hazard Codes Xn
Risk Statements 22-37/38-41
Safety Statements 26-39
TSCA Yes
HS Code 2933119000

2-Chloro-3-Methylpyrazine CAS#95-58-9 Product Application

2-Chloro-3-methylpyrazine is primarily used as an important intermediate in organic synthesis and pharmaceutical research. Its chlorinated pyrazine structure provides a versatile reactive site for further chemical modification, making it useful in the preparation of various substituted pyrazine derivatives and nitrogen-containing heterocyclic compounds. It is also utilized in medicinal chemistry research and pharmaceutical development, particularly as a building block for the synthesis of biologically active molecules and kinase inhibitor candidates. Additionally, the compound finds applications in laboratory research, synthetic chemistry, and the development of novel pharmaceutical intermediates.

2-Chloro-3-Methylpyrazine

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