5-Bromothiophenesulfonyl Chloride CAS#55854-46-1 Product Description
5-Bromothiophene-2-sulfonyl Chloride is a specialized brominated thiophene derivative containing both a sulfonyl chloride functional group and a bromine substituent. Its unique molecular structure makes it a valuable building block for organic synthesis and heterocyclic compound development.
The sulfonyl chloride group provides a reactive site for the preparation of sulfonamides and other sulfur-containing derivatives, while the bromine substituent offers an additional functionalization site for further chemical transformations.
This compound is particularly useful in medicinal chemistry research, pharmaceutical intermediate development, heterocyclic chemistry, and the synthesis of structurally diverse thiophene-based compounds.
With its versatile chemical structure, 5-Bromothiophene-2-sulfonyl Chloride serves as a useful synthetic intermediate for research laboratories, pharmaceutical R&D, and specialty chemical manufacturers.

5-Bromothiophenesulfonyl Chloride CAS#55854-46-1 Product Application
| Melting point | 40-44 °C (lit.) |
| Boiling point | 100-102 °C/0.5 mmHg (lit.) |
| density | 1.985±0.06 g/cm3(Predicted) |
| Fp | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| form | crystalline powder |
| color | Off-white/ faint lemon |
| Sensitive | Moisture Sensitive |
| CAS DataBase Reference | 55854-46-1(CAS DataBase Reference) |
5-Bromothiophenesulfonyl Chloride CAS#55854-46-1 Product Application
| Hazard Codes | C,Xi,Xn |
| Risk Statements | 34-43-36/37/38-20/21/22 |
| Safety Statements | 26-36/37/39-45-28A-25-36 |
| RIDADR | UN 3261 8/PG 2 |
| WGK Germany | 3 |
| Hazard Note | Harmful/Corrosive |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29349990 |
5-Bromothiophenesulfonyl Chloride CAS#55854-46-1 Product Application
1. Pharmaceutical Intermediate Synthesis
Used as a synthetic intermediate in pharmaceutical research and development.
Applied in the preparation of thiophene-containing pharmaceutical intermediates.
Used in the development of structurally diverse sulfur-containing compounds.
Serves as a building block for medicinal chemistry research.
Applied in the synthesis of potential biologically active molecules.
2. Sulfonamide Synthesis
Used as a precursor for the synthesis of sulfonamide derivatives.
Applied in the preparation of thiophene-based sulfonamides.
Used in the development of functionalized sulfonamide compounds.
Serves as a useful intermediate in sulfur-containing organic compound synthesis.
Applied in medicinal chemistry research involving sulfonamide structures.
3. Thiophene Derivatives Synthesis
Used in the synthesis of various thiophene-based derivatives.
Applied in the preparation of brominated thiophene compounds.
Used as a building block for functionalized heterocyclic molecules.
Supports the structural modification of thiophene-based compounds.
Applied in the development of novel sulfur- and nitrogen-containing heterocycles.
4. Organic Synthesis
Used as a versatile intermediate in organic synthesis.
Applied in the preparation of sulfonyl-containing organic compounds.
Used in the synthesis of functionalized aromatic compounds.
Provides reactive sites for further chemical transformations.
Applied in the development of structurally complex organic molecules.
5. Medicinal Chemistry Research
Used as a building block in medicinal chemistry research.
Applied in the synthesis of thiophene-containing candidate molecules.
Supports the development of structurally diverse bioactive compound libraries.
Used in the investigation of structure–activity relationships (SAR).
Applied in early-stage drug discovery research.
6. Heterocyclic Compound Synthesis
Used in the preparation of sulfur-containing heterocyclic compounds.
Applied in the synthesis of functionalized thiophene derivatives.
Serves as a building block for heterocyclic molecular development.
Used in research involving substituted aromatic heterocycles.
Supports the development of new heterocyclic structures.
7. Agrochemical Intermediate Research
Used as a potential synthetic building block in agrochemical research.
Applied in the development of functionalized thiophene-containing compounds.
Supports research into novel sulfur-containing heterocyclic structures.
May be investigated in the synthesis of specialized agrochemical intermediates.
8. Specialty Chemical Research
Used in the development of specialized sulfur-containing compounds.
Applied in the synthesis of functional organic materials.
Provides a versatile intermediate for molecular modification.
Used in research involving brominated heterocyclic building blocks.
