5-Methyl-2-Thiophenecarboxylic Acid CAS#1918-79-2 Product Description
5-Methyl-2-Thiophenecarboxylic Acid (CAS No. 1918-79-2) is an important thiophene derivative featuring a methyl-substituted heterocyclic ring and a carboxylic acid functional group. It is a versatile organic synthesis building block used in the preparation of various thiophene-based compounds and functionalized heterocyclic molecules.
With its distinctive thiophene structure and reactive carboxylic acid group, this compound provides a useful starting material for the synthesis of thiophene derivatives, carboxylic acid derivatives, and other specialty organic compounds.
5-Methyl-2-Thiophenecarboxylic Acid is suitable for organic synthesis, medicinal chemistry research, pharmaceutical intermediate development, and heterocyclic chemistry research. It is also useful in the development of novel functional molecules and specialized fine chemicals.

5-Methyl-2-Thiophenecarboxylic Acid CAS#1918-79-2 Chemical Properties
| Melting point | 135-138 °C(lit.) |
| Boiling point | 229.75°C (rough estimate) |
| density | 1.365 (estimate) |
| refractive index | 1.5300 (estimate) |
| storage temp. | 2-8°C(protect from light) |
| pka | 3.71±0.10(Predicted) |
| form | Liquid |
| color | Clear |
| BRN | 113857 |
| CAS DataBase Reference | 1918-79-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Methyl-2-thiophenecarboxylic acid (keto form) |
5-Methyl-2-Thiophenecarboxylic Acid CAS#1918-79-2 Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29309090 |
5-Methyl-2-Thiophenecarboxylic Acid CAS#1918-79-2 Product Application
1. Pharmaceutical Intermediate Synthesis
Used as an intermediate in the synthesis of thiophene-containing pharmaceutical compounds.
Serves as a building block for pharmaceutical research and development.
Applied in the preparation of functionalized thiophene derivatives for medicinal chemistry research.
Used in the development of novel heterocyclic pharmaceutical intermediates.
2. Thiophene Derivatives Synthesis
Used as a starting material for the synthesis of various thiophene derivatives.
Applied in the preparation of substituted thiophene compounds.
Serves as a building block for functionalized thiophene-based molecules.
Used in the development of structurally modified thiophene compounds.
3. Organic Synthesis
Used as a versatile building block in organic synthesis.
Applied in the preparation of carboxylic acid derivatives.
Used in the synthesis of functionalized aromatic heterocyclic compounds.
Serves as a precursor for the development of complex organic molecules.
4. Heterocyclic Compound Synthesis
Used in the synthesis of sulfur-containing heterocyclic compounds.
Applied in the development of substituted thiophene-based heterocycles.
Provides a useful scaffold for heterocyclic molecular design.
Used in heterocyclic chemistry research and molecular modification.
5. Medicinal Chemistry Research
Used as a synthetic building block in medicinal chemistry research.
Applied in the synthesis of thiophene-based candidate compounds.
Supports the development of structurally diverse compound libraries.
Used in structure–activity relationship (SAR) studies.
6. Fine Chemical Development
Used as a specialized intermediate in fine chemical synthesis.
Applied in the development of functional organic compounds.
Used as a starting material for specialty chemical research.
Supports the synthesis of novel thiophene-containing molecules.
7. Carboxylic Acid Derivatives Synthesis
Used in the preparation of functionalized carboxylic acid derivatives.
Applied in the synthesis of amides, esters, and other carboxylic acid derivatives.
Serves as a precursor for various thiophene-based organic compounds.
Supports research into structurally diverse functional molecules.
