2-Bromo-6-methoxypyridine CAS#40473-07-2

2-Bromo-6-methoxypyridine is a brominated nitrogen-containing heterocyclic organic compound with the molecular formula C₆H₆BrNO and a molecular weight of 188.02 g/mol. Its molecular structure consists of a pyridine ring substituted with a bromine atom at the second position and a methoxy group at the sixth position. The combination of these functional groups makes it a valuable building block in organic synthesis and pyridine-based compound development.

The compound is generally supplied as a clear, colorless to golden liquid. It has a reported density of approximately 1.53 g/mL at 25°C, a boiling point of around 206°C, and a refractive index of approximately 1.559. These physical characteristics make it suitable for identification and quality evaluation in laboratory and industrial chemical applications.

2-Bromo-6-methoxypyridine is primarily used as an organic synthesis intermediate. The bromine substituent provides a functional site for further chemical transformations, including suitable cross-coupling and substitution reactions. Meanwhile, the methoxy group contributes to the electronic and structural characteristics of the pyridine ring. This compound is particularly relevant to heterocyclic chemistry, pharmaceutical intermediate research, fine chemical manufacturing, and the preparation of functionalized pyridine derivatives. Its defined molecular structure and versatile reactivity make it a useful starting material for researchers and manufacturers developing specialty nitrogen-containing compounds.

Safety and Storage

2-Bromo-6-methoxypyridine should be handled in accordance with the supplier's Safety Data Sheet (SDS) and applicable chemical safety regulations. According to available Thermo Fisher and Acros Organics safety documentation, this substance is classified as harmful if swallowed, in contact with skin, or if inhaled. It may also cause skin irritation, serious eye irritation, and respiratory irritation. Avoid direct contact with the material and prevent inhalation of vapors during handling, sampling, or transfer operations.

Handle the product in a well-ventilated area, preferably under local exhaust ventilation. Wear suitable personal protective equipment, including chemical-resistant gloves, safety goggles, and protective clothing. Avoid eating, drinking, or smoking in areas where the substance is handled. Wash hands thoroughly after use and remove contaminated clothing before reuse. In case of skin contact, wash thoroughly with soap and water. If inhaled, move the affected person to fresh air. For eye exposure, rinse cautiously with water for several minutes and seek medical advice according to the SDS.

2-Bromo-6-methoxypyridine Chemical Properties

2-Bromo-6-methoxypyridine Chemical Properties

Safety Information