Product Overview
2-Hydroxynicotinic Acid, also known as 2-hydroxypyridine-3-carboxylic acid or 3-carboxy-2-pyridone, is a nitrogen-containing heterocyclic organic compound with the molecular formula C₆H₅NO₃ and a molecular weight of 139.11 g/mol. Its molecular structure features a pyridine-based six-membered ring with hydroxyl and carboxylic acid functionalities. The compound can also exist in a pyridone tautomeric form, making it an interesting substance for heterocyclic chemistry and organic synthesis research.
2-Hydroxynicotinic Acid is generally supplied as a white to light yellow powder or crystalline solid. It has a relatively high melting point of approximately 258–261°C. It is soluble in alkaline aqueous solutions, such as dilute sodium hydroxide, and its physical properties make it suitable for various laboratory synthesis and research applications.

Safety and Storage
2-Hydroxynicotinic Acid should be handled in accordance with the supplier's Safety Data Sheet (SDS) and applicable chemical safety regulations. Supplier safety documentation identifies potential hazards including skin irritation, serious eye irritation, and respiratory irritation. Hazard classifications may vary between suppliers and regulatory systems, so the SDS corresponding to the actual product and grade should always be consulted before handling.
Avoid inhaling dust and prevent direct contact with the eyes and skin. Handle the material in a well-ventilated area, preferably under local exhaust ventilation when weighing, transferring, or processing the powder. Wear appropriate personal protective equipment, including chemical-resistant gloves, safety goggles, and protective clothing. Avoid generating unnecessary dust and wash hands thoroughly after handling. Do not eat, drink, or smoke in areas where the chemical is used.
2-Hydroxynicotinic acid Chemical Properties
Melting point | 258-261 °C(lit.) |
Boiling point | 255.04°C (rough estimate) |
density | 1.4429 (rough estimate) |
refractive index | 1.5423 (estimate) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | 0.1 M NaOH: 0.1 g/mL, clear |
pka | 2.40±0.20(Predicted) |
form | Powder |
color | White to light yellow |
BRN | 119028 |
InChIKey | UEYQJQVBUVAELZ-UHFFFAOYSA-N |
CAS DataBase Reference | 609-71-2(CAS DataBase Reference) |
Safety Information
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-37/39 |
WGK Germany | 3 |
HazardClass | IRRITANT |
HS Code | 29333990 |