Product Overview
Calcium Gluconate (CAS 299-28-5) is an organic calcium salt formed from calcium and gluconic acid. It is commonly supplied as a white crystalline powder or granules and is known for its versatility across pharmaceutical, food, cosmetic, and specialty chemical applications. Its molecular formula is C₁₂H₂₂CaO₁₄, with a molecular weight of 430.37 g/mol.
Calcium Gluconate is valued as a source of calcium ions in various formulation systems. Compared with some other calcium salts, it offers a different balance of solubility and formulation characteristics. It is slightly soluble in cold water, while its solubility increases in hot water. This property makes it suitable for selected aqueous processing and formulation applications.
In the food industry, Calcium Gluconate may be used as a calcium fortification ingredient, stabilizer, or processing aid, subject to applicable regulations and product grade. In pharmaceutical applications, it is used as a calcium-containing ingredient in appropriate formulations. It is also utilized in cosmetic formulations and chemical research. Product specifications, purity, and suitability should always be confirmed according to the intended application.

Safety and Storage
Calcium Gluconate should be handled according to the safety requirements of its specific grade and supplier documentation. Although it is commonly used in food and pharmaceutical-related applications, this does not mean that every commercial grade is suitable for direct consumption or medical use. Always verify the product specification, applicable certifications, and Safety Data Sheet (SDS) before selecting it for a particular purpose.
During routine handling, avoid generating or inhaling excessive dust. Use appropriate personal protective equipment, including safety glasses, protective gloves, and suitable work clothing. Handle the powder in a well-ventilated area, especially during weighing, mixing, or transfer operations. Avoid unnecessary contact with the eyes and prolonged contact with the skin. Wash hands thoroughly after handling and do not eat, drink, or smoke in the working area.
Store Calcium Gluconate in a tightly sealed container in a cool, dry, and well-ventilated place. Protect it from excessive moisture, heat, and contamination. Keep containers properly labeled and away from incompatible materials, particularly strong oxidizing agents. Follow the supplier's recommended storage temperature and handling instructions for the specific product grade. In case of accidental release, avoid creating airborne dust and collect the material using appropriate protective equipment. Dispose of unused material and packaging in accordance with local regulations.
Calcium gluconate Chemical Properties
Melting point | 195°C |
10.2 º (c=1, H2O 22 ºC) | |
Boiling point | 400℃[at 101 325 Pa] |
density | 1.677[at 20℃] |
vapor pressure | 0.004Pa at 20℃ |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Sparingly soluble in water, freely soluble in boiling water. |
form | Crystals or Crystalline Powder |
color | White |
PH | pH;6.0~8.0 |
Odor | at 100.00?%. odorless |
Water Solubility | 3.3 g/100mL |
Hydrolytic Sensitivity | 0: forms stable aqueous solutions |
Merck | 14,1669 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
InChIKey | KYUVBRZSDFBLTH-OSQBQZLYSA-M |
LogP | -5.31 at 20℃ |
CAS DataBase Reference | 299-28-5(CAS DataBase Reference) |
EPA Substance Registry System | D-Gluconic acid, calcium salt (2:1) (299-28-5) |