Calcium gluconate

  • Reliable Calcium Source: Provides calcium in a gluconate salt form for various formulations.

  • Established Chemical Identity: A well-characterized calcium salt with a recognized CAS number.

  • Versatile Applications: Suitable for food, pharmaceutical, cosmetic, and chemical research applications, depending on grade.

  • Stable Composition: Generally stable under recommended storage conditions.

  • Flexible Formulation: Can be incorporated into different solid and liquid formulation systems.

  • Multiple Industry Uses: Serves as a calcium source, formulation ingredient, and chelating-related component.

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Product Overview

Calcium Gluconate (CAS 299-28-5) is an organic calcium salt formed from calcium and gluconic acid. It is commonly supplied as a white crystalline powder or granules and is known for its versatility across pharmaceutical, food, cosmetic, and specialty chemical applications. Its molecular formula is C₁₂H₂₂CaO₁₄, with a molecular weight of 430.37 g/mol.

Calcium Gluconate is valued as a source of calcium ions in various formulation systems. Compared with some other calcium salts, it offers a different balance of solubility and formulation characteristics. It is slightly soluble in cold water, while its solubility increases in hot water. This property makes it suitable for selected aqueous processing and formulation applications.

In the food industry, Calcium Gluconate may be used as a calcium fortification ingredient, stabilizer, or processing aid, subject to applicable regulations and product grade. In pharmaceutical applications, it is used as a calcium-containing ingredient in appropriate formulations. It is also utilized in cosmetic formulations and chemical research. Product specifications, purity, and suitability should always be confirmed according to the intended application.

CAS 299-28-5

Safety and Storage

Calcium Gluconate should be handled according to the safety requirements of its specific grade and supplier documentation. Although it is commonly used in food and pharmaceutical-related applications, this does not mean that every commercial grade is suitable for direct consumption or medical use. Always verify the product specification, applicable certifications, and Safety Data Sheet (SDS) before selecting it for a particular purpose.

During routine handling, avoid generating or inhaling excessive dust. Use appropriate personal protective equipment, including safety glasses, protective gloves, and suitable work clothing. Handle the powder in a well-ventilated area, especially during weighing, mixing, or transfer operations. Avoid unnecessary contact with the eyes and prolonged contact with the skin. Wash hands thoroughly after handling and do not eat, drink, or smoke in the working area.

Store Calcium Gluconate in a tightly sealed container in a cool, dry, and well-ventilated place. Protect it from excessive moisture, heat, and contamination. Keep containers properly labeled and away from incompatible materials, particularly strong oxidizing agents. Follow the supplier's recommended storage temperature and handling instructions for the specific product grade. In case of accidental release, avoid creating airborne dust and collect the material using appropriate protective equipment. Dispose of unused material and packaging in accordance with local regulations.

Calcium gluconate Chemical Properties

Melting point 

195°C

alpha 

10.2 º (c=1, H2O 22 ºC)

Boiling point 

400℃[at 101 325 Pa]

density 

1.677[at 20℃]

vapor pressure 

0.004Pa at 20℃

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Sparingly soluble in water, freely soluble in boiling water.

form 

Crystals or Crystalline Powder

color 

White

PH

pH;6.0~8.0

Odor

at 100.00?%. odorless

Water Solubility 

3.3 g/100mL

Hydrolytic Sensitivity

0: forms stable aqueous solutions

Merck 

14,1669

Stability:

Stable. Incompatible with strong oxidizing agents.

InChIKey

KYUVBRZSDFBLTH-OSQBQZLYSA-M

LogP

-5.31 at 20℃

CAS DataBase Reference

299-28-5(CAS DataBase Reference)

EPA Substance Registry System

D-Gluconic acid, calcium salt (2:1) (299-28-5)

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