Product Overview
6-Chloro-9-(tetrahydro-2-pyranyl)purine (CAS 7306-68-5) is a substituted purine compound containing a chlorine atom at the 6-position and a tetrahydro-2-pyranyl (THP) group attached to the N9 position of the purine ring. Its molecular formula is C₁₀H₁₁ClN₄O, and its molecular weight is approximately 238.67 g/mol. The product is generally described as a white to pale yellow solid, with a reported melting point of approximately 149–151°C.
The THP group serves as a protecting group in organic synthesis, helping modify the reactivity of the purine nitrogen during selected chemical transformations. The chlorine substituent at the 6-position provides a functional site for further substitution reactions, making this compound a useful building block for preparing other purine derivatives. It has been reported as an intermediate in the synthesis of substituted purine compounds, including 6-substituted purine derivatives.
This material is primarily intended for chemical synthesis, pharmaceutical intermediate development, heterocyclic chemistry, and laboratory research. Its structural features make it useful for researchers developing functionalized purine compounds and exploring related synthetic pathways. Actual suitability depends on the required purity, analytical specifications, and intended synthetic process.
Main Applications
Pharmaceutical Intermediate Synthesis: Used as a starting material for preparing substituted purine compounds.
Purine Derivative Development: Supports the synthesis of structurally modified purine molecules.
Organic Synthesis: Used in substitution reactions involving the 6-chloro position.
Heterocyclic Chemistry: Serves as a functionalized purine building block.
Chemical Research: Applied in laboratory studies involving purine chemistry and protecting-group strategies.
Fine Chemical Development: Used in the preparation of specialty heterocyclic compounds.
6-CHLORO-9-(TETRAHYDRO-2-PYRANYL)-PURINE Chemical Properties
Melting point | 149-151℃ |
Boiling point | 428.3±55.0 °C(Predicted) |
density | 1.604 |
Fp | 213°(415°F) |
refractive index | 1.7410 |
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
pka | 0.79±0.10(Predicted) |
form | Solid |
color | White to pale yellow |
CAS DataBase Reference | 7306-68-5(CAS DataBase Reference) |
Safety Information
HS Code | 2933998090 |
