Products Description
N,N-Dimethylaniline(DMA)isapaleyellowtolightbrownoilyliquidcharacterizedbyapungentodor.Itissolubleinorganicsolventssuchasethanol,chloroform,ether,andaromatichydrocarbons,butexhibitsverylimitedsolubilityinwater.Asatertiaryaromaticamine,itiswidelyusedasanintermediateinthesynthesisofvarioustriarylmethanedyes,includingmalachitegreen.Inaddition,itisemployedinthepreparationofreagentsusedinGramstaining,acommonmicrobiologicaltechniquefordifferentiatingbacteriabasedontheircellwallcharacteristics.
Chemical Properties
Melting point | 1.5-2.5 °C (lit.) |
Boiling point | 193-194 °C (lit.) |
density | 0.956 g/mL at 25 °C (lit.) |
vapor density | 3 (vs air) |
vapor pressure | 2 mm Hg ( 25 °C) |
refractive index | n20/D |
Fp | 158 °F |
storage temp. | Store below +30°C. |
solubility | 1.2g/l |
pka | 5.15(at 25℃) |
form | Liquid |
color | Clear yellow |
Relative polarity | 0.179 |
PH | 7.4 (1.2g/l, H2O, 20℃) |
explosive limit | 1.2-7%(V) |
Water Solubility | 1 g/L (20 ºC) |
Merck | 14,3234 |
BRN | 507140 |
Henry's Law Constant | 4.98(x 10-6 atm?m3/mol) at 20 °C (approximate - calculated from water solubility and vapor pressure) |
Exposure limits | NIOSH REL: TWA 5 ppm (25 mg/m3), STEL 10 ppm (50 mg/m3), IDLH 100 ppm; OSHA PEL: TWA 5 ppm; ACGIH TLV: TWA 5 ppm, STEL 10 ppm (adopted). |
Dielectric constant | 4.4000000000000004 |
Stability: | Stable. Incompatible with strong oxidizing agents, strong acids, acid chlorides, acid anhydrides, chloroformates, halogens. Combustible. |
InChIKey | JLTDJTHDQAWBAV-UHFFFAOYSA-N |
LogP | 1.171 at 35℃ |
CAS DataBase Reference | 121-69-7(CAS DataBase Reference) |
IARC | 3 (Vol. 57) 1993 |
NIST Chemistry Reference | Benzenamine, N,N-dimethyl-(121-69-7) |
EPA Substance Registry System | N,N-Dimethylaniline (121-69-7) |
Safety Information
Hazard Codes | T,N |
Risk Statements | 61-20/21-51/53-40-23/24/25 |
Safety Statements | 53-45-61-36/37-28A-28 |
RIDADR | UN 2253 6.1/PG 2 |
OEB | A |
OEL | TWA: 5 ppm (25 mg/m3), STEL: 10 ppm (50 mg/m3) [skin] |
WGK Germany | 3 |
RTECS | BX4725000 |
F | 8 |
Autoignition Temperature | 370 °C DIN 51794 |
TSCA | Yes |
HS Code | 2921 42 00 |
HazardClass | 6.1 |
PackingGroup | II |
Hazardous Substances Data | 121-69-7(Hazardous Substances Data) |
Toxicity | LD50 orally in rats: 1.41 ml/kg (Smyth) |
IDLA | 100 ppm |
Product Applications
N,N-Dimethylaniline is an important chemical intermediate widely used in the production of dyes and pigments. It serves as a key raw material in the synthesis of various dyes, including alkaline yellow, Crystal Violet 5BN, Basic Magenta Green, Lake Blue BB, Basic Brilliant Blue R, Cationic Red 2BL, Brilliant Red 5GN, Violet 3BL, and Brilliant Blue. In the pharmaceutical industry, it is also used as an intermediate in the manufacture of several pharmaceutical compounds, such as cefazolin V, sulfamonomethoxine, sulfadoxine, and flucytosine. Furthermore, N,N-dimethylaniline can be utilized in the synthesis of vanillin, as a stabilizer in colorimetric peroxidase determination, and as a reagent in various chemical synthesis processes.
In addition to these applications, N,N-dimethylaniline is employed in the manufacture of dyestuffs, as an organic solvent, as a reagent in methylation reactions, and as a curing agent for fiberglass-reinforced resin systems.
