Products Description
4-Fluorobenzaldehyde, also called p-Fluorobenzaldehyde, CAS 459-57-4, is a colourless to pale yellow transparent aromatic aldehyde liquid with molecular formula C₇H₅FO. It is a key fluorinated fine chemical intermediate. The fluorine atom on the para position adjusts the electronic property of benzene ring, bringing distinctive reaction characteristics. It is mainly supplied with 99% purity. It is sensitive to air and needs sealed storage. It is widely adopted in pharmaceutical, agrochemical, liquid crystal and dye synthesis. We can provide lab test samples and bulk shipment, with full quality documents for global customers.
Parameters
| Melting point | -10 °C (lit.) |
| Boiling point | 181 °C/758 mmHg (lit.) |
| density | 1.157 g/mL at 25 °C (lit.) |
| vapor pressure | 19 hPa (70 °C) |
| refractive index | n |
| Fp | 134 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform, Methanol |
| form | Liquid |
| color | Clear colorless to yellow |
| Specific Gravity | 1.157 |
| Water Solubility | IMMISCIBLE |
| Sensitive | Air Sensitive |
| BRN | 385857 |
| Stability: | Air Sensitive |
| InChIKey | UOQXIWFBQSVDPP-UHFFFAOYSA-N |
| CAS DataBase Reference | 459-57-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzaldehyde, 4-fluoro-(459-57-4) |
| EPA Substance Registry System | Benzaldehyde, 4-fluoro- (459-57-4) |
Safety Information
| Hazard Codes | Xi,F |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-37/39-36/37/39-27 |
| RIDADR | UN 1989 3/PG 3 |
| WGK Germany | 2 |
| F | 9-23 |
| Hazard Note | Flammable |
| TSCA | T |
| HazardClass | 3.2 |
| PackingGroup | III |
| HS Code | 29130000 |
Product Application
As a fluorine-substituted variant of benzaldehyde, 4-Fluorobenzaldehyde carries a verified inhibitory effect on mushroom tyrosinase, making it a valuable lead structure for enzyme inhibitor development. It is a key raw material deployed in the production of pyrazolopyridine derivatives, which are developed as mitogen-activated protein kinase (MAPK) inhibitors for targeted therapeutic use. This compound also stands as an essential intermediate widely adopted across the synthesis workflows of numerous pharmaceutical products.
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