Products Description
Chlorhexidine is widely used for the prevention and treatment of various oral infections, including gingivitis (such as acute necrotizing ulcerative gingivitis), post-dental surgery oral infections, and oral infections in patients with cancer and leukemia. It is also applied in the treatment of stomatitis and follicular stomatitis caused by bacterial or fungal infections, including those associated with denture wear.
In addition, Chlorhexidine helps reduce dental plaque and can be used as a disinfectant for medical instruments and skin, as well as a preservative in eye drop formulations.
Product Parameters
| Name | Chlorhexidine |
| CAS | No.55-56-1 |
| CID | 9552079 |
| EINECS(EC#) | 223-026-6; 200-238-7; 200-302-4 |
| Molecular Formula | C22H30Cl2N10 (isomer) |
| Inchi | InChI=1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34) |
| InChIkey | GHXZTYHSJHQHIJ-UHFFFAOYSA-N |
| Canonical Smiles | C1=CC(=CC=C1NC(=NC(=NCCCCCCN=C(N)N=C(N)NC2=CC=C(C=C2)Cl)N)N)Cl |
| Isomers Smiles | C1=CC(=CC=C1N/C(=N/C(=NCCCCCCN=C(/N=C(/NC2=CC=C(C=C2)Cl)\N)N)N)/N)Cl |
| Density | 1.1555 (rough estimate) |
| Melting point | 134-136 °C(lit.) |
| Boiling point | 641.45°C (rough estimate) |
| Refractive index | 1.6300 (estimate) |
| Flash Point | 376.7°C |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Precise Quality | 564.224 |
| PSA | 204.88 |
| logP | 6.3747 |
| Solubility | 0.08 g/100 mL (20 oC) |
| Appearance | white powder |
| Chemical Properties | Chlorhexidine occurs as an odorless, bitter tasting, white crystallinepowder. |
| Color/Form | Crystals from methanol Solid |
| pKa | pKa 10.78 (Uncertain) |
| Water Solubility | 0.08 g/100 mL (20 oC) |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| StorageTemp | Keep tightly closed. |
Product Application
Chlorhexidine is widely used for the prevention and treatment of gingivitis (including acute necrotizing ulcerative gingivitis), oral infections following dental surgery, and oral infections in patients with cancer and leukemia. It is also applied for the treatment of stomatitis and follicular stomatitis caused by bacterial or fungal oral infections related to denture wear. In addition, it helps reduce dental plaque and can be used as a disinfectant for instruments and skin, as well as a preservative in eye drop formulations.
As a surfactant-type antimicrobial agent, Chlorhexidine exhibits strong broad-spectrum antibacterial and bactericidal activity. It is effective against both Gram-positive and Gram-negative bacteria, making it suitable for various disinfection and antimicrobial applications.
