Product Description of Benzyldimethylhexadecylammonium Chloride (CAS# 122-18-9)
Benzyldimethylhexadecylammonium chloride, commonly referred to as cetalkonium chloride, is a cationic quaternary ammonium surfactant and a key component of benzalkonium chloride formulations. Benzalkonium chloride itself represents a blend of alkylbenzyl dimethyl ammonium derivatives, primarily featuring n-C12H25 (dodecyl), n-C14H29 (tetradecyl), and n-C16H33 (hexadecyl) carbon chains. Distinguished by its pronounced lipophilicity and limited aqueous solubility, cetalkonium chloride functions effectively as an antimicrobial agent, surfactant, and pharmaceutical excipient. Utilizing its preservative properties, this quaternary ammonium compound is routinely incorporated into research targeting oral, throat, and ocular infections, while serving as a pharmaceutical raw material centered on anti-inflammatory activity.
Benzyldimethylhexadecylammonium chloride Chemical Properties
| Melting point | 55-65 °C(lit.) |
| Boiling point | 550.14°C (rough estimate) |
| Density | 0.9089 (rough estimate) |
| Vapor pressure | 0Pa at 25℃ |
| Refractive index | 1.6000 (estimate) |
| Storage temp. | room temp |
| Solubility | DMSO: 100 mg/mL (252.47 mM) |
| Form | Powder |
| Color | White to creamy-white |
| Water Solubility | MODERATELY SOLUBLE |
| Merck | 142,017 |
| BRN | 3802341 |
| LogP | 3.022 at 25℃ |
| CAS DataBase Reference | 122-18-9(CAS DataBase Reference) |
| EPA Substance Registry System | Benzyl hexadecyl dimethyl ammonium chloride (122-18-9) |
Safety Information
| Hazard Codes | Xi,N,C |
| Risk Statements | 36/37/38-50/53-50-34-21/22 |
| Safety Statements | 61-45-36/37/39-26-60 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 3 |
| RTECS | BO6822450 |
| F | 3 |
| TSCA | Yes |
| HazardClass | 8 |
| HS Code | 29239000 |
| Toxicity | eye-rbt 150 mg MLD ARZNAD 9,349,59 |
| Hazard Codes | Xi,N,C |
| Risk Statements | 36/37/38-50/53-50-34-21/22 |
| Safety Statements | 61-45-36/37/39-26-60 |
| RIDADR | UN 3077 9/PG 3 |
Product Application of Benzyldimethylhexadecylammonium Chloride (CAS# 122-18-9)
Primary Pharmaceutical Utility: Serves as a fundamental raw material in active pharmaceutical ingredients and excipient formulations.
Broad Industrial & Chemical Uses: Operates effectively as a phase-transfer catalyst, specialized emulsifier, and antistatic agent in industrial processing.
Sanitation & Biocidal Performance: Widely deployed as a disinfectant base and bactericidal agent for antimicrobial sanitization.
