2-Amino-3-Chloropyrazine CAS#6863-73-6 Product Description
2-Chloro-3-aminopyrazine is a nitrogen-containing heterocyclic organic compound widely used as an important intermediate in pharmaceutical research, organic synthesis, and chemical manufacturing. Its molecular formula is C₄H₄ClN₃. The molecular structure consists of a pyrazine ring substituted with both a chlorine atom and an amino group, providing versatile reactive sites for further chemical transformations and molecular functionalization. These structural characteristics make it a useful building block for the preparation of various pyrazine derivatives, heterocyclic compounds, and pharmaceutical intermediates.
Under normal conditions, 2-Chloro-3-aminopyrazine generally appears as a white to pale yellow or dark green powder or crystalline solid. Its reported melting point ranges from 167 to 171°C, while its boiling point is approximately 248.1°C at 760 mmHg. In terms of solubility, the compound is slightly soluble in water, a property that may be relevant to its handling, formulation, and purification during laboratory synthesis.
Owing to its distinctive heterocyclic structure and the presence of amino and chloro functional groups, 2-Chloro-3-aminopyrazine offers opportunities for further substitution reactions and chemical derivatization. It is therefore a valuable synthetic building block in medicinal chemistry, pharmaceutical intermediate development, and the preparation of specialized organic chemicals. Its applications extend to laboratory research and development, as well as various chemical and pharmaceutical production processes.
2-Amino-3-Chloropyrazine CAS#6863-73-6 Chemical Properties
| Melting point | 167-171°C |
| Boiling point | 248.1±35.0 °C(Predicted) |
| density | 1.437±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 2.37±0.10(Predicted) |
| color | White to Light yellow to Dark green |
| Water Solubility | Slightly soluble in water. |
| InChIKey | AEVSSZHXGJAPIE-UHFFFAOYSA-N |
| CAS DataBase Reference | 6863-73-6 |
2-Amino-3-Chloropyrazine CAS#6863-73-6 Safety Information
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37 |
| HazardClass | IRRITANT |
| HS Code | 29339900 |
2-Amino-3-Chloropyrazine CAS#6863-73-6 Product Application
2-Chloro-3-aminopyrazine can also be used as a chemical building block in research involving the preparation of cesium adsorption materials based on sodium-modified zeolites. Such materials are investigated for their potential application in cesium ion adsorption and separation processes. This provides an additional area of interest for 2-Chloro-3-aminopyrazine beyond its conventional applications in organic synthesis and pharmaceutical intermediate development, highlighting its potential relevance to functional material preparation and adsorption-related research.
