Aminopyrazine CAS#5049-61-6 Product Description
Aminopyrazine is an important nitrogen-containing heterocyclic compound widely used as a key intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a valuable starting material and reaction matrix for the four-component synthesis of imidazolidinedione derivatives, providing a useful platform for constructing structurally diverse heterocyclic compounds. In addition, aminopyrazine is widely employed in the preparation of pharmaceutical intermediates and other fine chemicals. Its pyrazine ring, containing two nitrogen atoms and an amino functional group, offers opportunities for various chemical transformations, functionalization, and molecular modification. Owing to its versatile reactivity and structural characteristics, aminopyrazine plays a useful role in medicinal chemistry research, heterocyclic compound synthesis, and the development of pharmaceutical building blocks.
Aminopyrazine CAS#5049-61-6 Chemical Properties
| Melting point | 118-120 °C (lit.) |
| Boiling point | 167.6°C (rough estimate) |
| Density | 1.1031 (rough estimate) |
| Refractive index | 1.5200 (estimate) |
| Storage temp | Keep in dark place,Inert atmosphere,Room temperature |
| Solubility | soluble in Methanol |
| Pka | 3.22±0.10(Predicted) |
| Form | Crystalline Powder |
| Color | Slightly yellow to beige |
| Water Solubility | soluble |
| BRN | 107025 |
| InChIKey | XFTQRUTUGRCSGO-UHFFFAOYSA-N |
| LogP | -0.07 |
| CAS DataBase Reference | 5049-61-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Aminopyrazine(5049-61-6) |
Aminopyrazine CAS#5049-61-6 Safety Information
| Hazard Codes | Xi,F |
| Risk Statements | 36/37/38-11 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 3 |
| HS Code | 29339990 |
Aminopyrazine CAS#5049-61-6 Product Application
Aminopyrazine is an important nitrogen-containing heterocyclic compound widely used as an intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a useful starting material for the four-component synthesis of imidazolidinedione derivatives, providing a versatile platform for the preparation of structurally diverse heterocyclic compounds. In addition, aminopyrazine is primarily utilized in laboratory research and development (R&D), biochemical research, and various biochemical production processes. Its distinctive pyrazine ring structure and amino functional group offer opportunities for further chemical modification and molecular derivatization, making it a valuable building block in medicinal chemistry, pharmaceutical intermediate development, and heterocyclic compound synthesis.
