2-Lodothiophene CAS#3437-95-4 Chemical Properties
Melting point | -40 °C (lit.) |
Boiling point | 73 °C/15 mmHg (lit.) |
density | 1.902 g/mL at 25 °C (lit.) |
refractive index | n20/D 1.651(lit.) |
Fp | 160 °F |
storage temp. | 2-8°C |
form | Liquid |
Specific Gravity | 1.902 |
color | Clear yellow-green to red-brown |
Sensitive | Light Sensitive |
BRN | 104666 |
InChIKey | ROIMNSWDOJCBFR-UHFFFAOYSA-N |
CAS DataBase Reference | 3437-95-4(CAS DataBase Reference) |
NIST Chemistry Reference | Thiophene, 2-iodo-(3437-95-4) |
EPA Substance Registry System | Thiophene, 2-iodo- (3437-95-4) |
Safety Information
Hazard Codes | Xn,Xi |
Risk Statements | 22-37/38-41-43-20/21/22-36/37/38 |
Safety Statements | 26-36/37/39-36/37-27 |
WGK Germany | 3 |
F | 3 |
TSCA | T |
HazardClass | IRRITANT |
HS Code | 29349990 |
Product Overview
2-Iodothiophene is a halogenated heterocyclic organic compound consisting of a thiophene ring substituted with an iodine atom at the 2-position. Its molecular structure combines the aromatic properties of thiophene with the chemical reactivity of the carbon-iodine bond.
It is an important building block in organic synthesis and is commonly used in the preparation of substituted thiophenes and other sulfur-containing organic compounds. Its iodine functional group makes it suitable for various carbon-carbon bond-forming reactions, including palladium-catalyzed cross-coupling reactions.
Product Manufacturing Process
Commercial production generally involves the preparation of iodinated thiophene derivatives through controlled halogenation or related organic synthesis processes, followed by separation, purification, and quality control. Specific manufacturing methods depend on the supplier's process and product specifications.
Main Applications
Pharmaceutical and medicinal chemistry research