Product Overview
5-Bromo-2-pyridinecarboxylic Acid (CAS 30766-11-1), also known as 5-Bromopicolinic Acid or 5-Bromopyridine-2-carboxylic Acid, is a brominated pyridine derivative used as an intermediate in organic synthesis and heterocyclic chemistry. Its molecular formula is C₆H₄BrNO₂, and its molecular weight is 202.01 g/mol. The material is generally supplied as a white to off-white powder, with a reported melting point of approximately 173–175°C.
The molecular structure contains two important functional features: a bromine atom at the 5-position of the pyridine ring and a carboxylic acid group at the 2-position. These functional groups provide opportunities for further chemical modification. The bromine substituent can participate in selected cross-coupling and substitution reactions, while the carboxylic acid group can be used in esterification, amidation, and other derivatization processes.
Safety and Storage
5-Bromo-2-pyridinecarboxylic Acid should be handled in accordance with the supplier's Safety Data Sheet (SDS) and applicable laboratory safety procedures. Available supplier documentation identifies potential hazards including skin irritation, serious eye irritation, and respiratory tract irritation. Some product classifications also indicate that the substance may be harmful if swallowed. Although it is commonly supplied as a solid powder, dust formation should be minimized during weighing, transfer, sampling, and mixing operations.
Wear suitable personal protective equipment, including chemical-resistant gloves, safety goggles, and protective clothing. Handle the material in a well-ventilated area or under local exhaust ventilation. Avoid breathing dust and prevent direct contact with skin and eyes. Wash hands thoroughly after handling, and remove contaminated clothing before reuse. In case of eye contact, rinse cautiously with water for several minutes and seek medical attention if irritation continues. If inhaled, move the affected person to fresh air and obtain medical advice if symptoms develop.
5-Bromo-2-pyridinecarboxylic Acid Chemical Properties
Melting point | 173-175°C |
Boiling point | 319.5±27.0 °C(Predicted) |
density | 1.813±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Soluble in methanol. |
form | Powder |
pka | 3.41±0.10(Predicted) |
color | White to off-white |
InChIKey | MNNQIBXLAHVDDL-UHFFFAOYSA-N |
CAS DataBase Reference | 30766-11-1(CAS DataBase Reference) |
Safety Information
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 24/25-36-26-37/39 |
HazardClass | IRRITANT |
HS Code | 29333990 |
