Products Description of Guanidine Hydrochloride 99.5% CAS#50-01-1
Also named carbamidine hydrochloride, guanidine hydrochloride takes the form of a white to pale-yellow crystalline solid and is practically insoluble in acetone, benzene, and ether. It finds broad use as an intermediate when synthesizing pharmaceuticals, pesticides, dyes, and other organic compounds. As a key starting material it underpins the manufacture of several medicines—sulfadiazine, sulfamethylpyrimidine, and sulfadimethylpyrimidine among them—as well as folic acid, and it additionally works as an antistatic agent on synthetic fibers.
Product Parameters of Guanidinehydrochloride99.5%CAS#50-01-1
| CAS | No. 50-01-1 |
| CID | 5742 |
| EINECS(EC#) | 200-002-3 |
| Molecular Formula | CH6ClN3 (isomer) |
| Inchi | InChI=1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H |
| InChIkey | PJJJBBJSCAKJQF-UHFFFAOYSA-N |
| Canonical Smiles | C(=N)(N)N.Cl |
| Isomers Smiles | C(=N)(N)N.Cl |
| Density | 1.18 g/mL at 25 °C(lit.) |
| Melting point | 180-185 °C(lit.) |
| Boiling point | 132.9 °C at 760 mmHg |
| Refractive index | n20/D 1.465 |
| Flash Point | 34.2 °C |
| Precise Quality | 95.025 |
| PSA | 75.89 |
| logP | 1.1409 |
| Solubility | H2O: 6?M, clear, colorless |
| Appearance | DryPowder; DryPowder, Liquid |
| Storage | Store at RT. |
| Chemical Properties | White cryst. powder |
| Color/Form | White to slightly yellow |
| Odo | Odorless |
| PH | 4.5-5.5 (100g/l, H2O, 20℃) |
| Water Solubility | H2O: 2280 g/L (20 oC) |
| Stability | Stable. Hygroscopic. Incompatible with strong oxidizing agents. |
| StorageTemp | Store at RT. |
Product Application of Guanidine Hydrochloride 99.5% CAS#50-01-1
In organic synthesis, guanidine hydrochloride serves as an intermediate for pharmaceuticals, pesticides, dyes, and various other chemical products. It is employed to prepare 2-aminopyrimidine, 2-amino-6-methylpyrimidine, and 2-amino-4,6-dimethylpyrimidine, and occupies an intermediate position in the sulfa-drug line covering sulfadiazine, sulfamethylpyrimidine, and sulfamethazine.
On reaction with ethyl cyanoacetate—using either guanidine hydrochloride or guanidine nitrate—it yields 2,4-diamino-6-hydroxypyrimidine, which is then converted into folic acid, the anti-anemia medicine. The compound also doubles as an antistatic agent for synthetic fibers.
