6-Chloroquinoline CAS#612-57-7 Product Description
6-Chloroquinoline (CAS No. 612-57-7) is a chlorinated quinoline derivative classified as a haloquinoline organic compound, with the molecular formula C₉H₆ClN and a molecular weight of 163.60 g/mol. It typically occurs as a white to pale yellow or orange-colored powder, depending on its physical state and purity. As an important nitrogen-containing heterocyclic building block, 6-Chloroquinoline is primarily employed as a pharmaceutical intermediate in organic synthesis and medicinal chemistry. It plays a valuable role in the preparation of various biologically relevant heterocyclic compounds, particularly 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine, as well as other quinoline-based derivatives and structurally diverse compounds. Its chloro-substituted quinoline framework provides a useful starting structure for further chemical transformations, making it a valuable intermediate in the development and synthesis of complex organic molecules.
6-Chloroquinoline CAS#612-57-7 Chemical Properties
| Melting point | 41-43 °C (lit.) |
| Boiling point | 126-127 °C/10 mmHg (lit.) |
| Density | 1.2108 (rough estimate) |
| Refractive index | 1.6110 (estimate) |
| Fp | >230 °F |
| Storage temp | Inert atmosphere,Room Temperature |
| Form | powder to lump |
| Pka | 4.18±0.10(Predicted) |
| Color | White to Light yellow to Light orange |
| Water Solubility | Insoluble in water. |
| BRN | 112963 |
| InChIKey | GKJSZXGYFJBYRQ-UHFFFAOYSA-N |
| CAS DataBase Reference | 612-57-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Quinoline, 6-chloro-,(612-57-7) |
| EPA Substance Registry System | Quinoline, 6-chloro- (612-57-7) |
6-Chloroquinoline CAS#612-57-7 Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29334900 |
6-Chloroquinoline CAS#612-57-7 Product Application
6-Chloroquinoline is a nitrogen-containing heterocyclic organic compound with the molecular formula C₉H₆ClN. It is widely utilized as a chemical reagent and versatile synthetic building block in various research and organic synthesis applications. Owing to its chloro-substituted quinoline structure, this compound serves as a useful intermediate for further chemical modifications and the preparation of diverse heterocyclic derivatives. It is particularly valuable in laboratory research, medicinal chemistry, and the development of novel organic compounds.
