Products Description
Ethanolamine is a viscous, hygroscopic amino alcohol that contains both amine and hydroxyl functional groups. It is widely distributed throughout the human body and is also a component of lecithin. Owing to its versatile chemical properties, ethanolamine has numerous industrial and commercial applications. It is commonly used in the production of agricultural chemicals, such as ammonia, as well as pharmaceuticals and detergents. Furthermore, it serves as a surfactant, a fluorimetric reagent, and an absorption agent for removing carbon dioxide (CO₂) and hydrogen sulfide (H₂S). In the pharmaceutical industry, ethanolamine is employed as a vascular sclerosing agent. It also exhibits antihistaminic activity, helping to relieve adverse symptoms associated with H1-receptor activation.
Chemical Properties
Melting point | 10-11 °C(lit.) |
Boiling point | 170 °C(lit.) |
density | 1.012 g/mL at 25 °C(lit.) |
vapor density | 2.1 (vs air) |
vapor pressure | 0.2 mm Hg ( 20 °C) |
refractive index | n20/D |
Fp | 200 °F |
storage temp. | Store at +15°C to +25°C. |
solubility | Soluble in benzene, ether, carbon tetrachloride. |
pka | 9.5(at 25℃) |
form | Liquid |
color | APHA: ≤15 |
Specific Gravity | 1.012 |
Relative polarity | 0.651 |
PH | 12.1 (100g/l, H2O, 20℃) |
Odor | ammoniacal odor |
explosive limit | 3.4-27%(V) |
Water Solubility | miscible |
Sensitive | Air Sensitive & Hygroscopic |
Merck | 14,3727 |
BRN | 505944 |
Henry's Law Constant | 1.61(x 10-10 atm?m3/mol) at 20 °C (Bone et al., 1983) |
Exposure limits | TLV-TWA 3 ppm (～7.5 mg/m3) (ACGIH, MSHA, and OSHA); TLV-STEL 6 ppm (～15 mg/m3) (ACGIH); IDLH 1000 ppm (NIOSH). |
Dielectric constant | 31.940000000000001 |
Stability: | Stable. Flammable; incompatible with strong oxidizing agents, strong acids. Hygroscopic. |
InChIKey | HZAXFHJVJLSVMW-UHFFFAOYSA-N |
LogP | -2.3--1.91 at 25℃ |
CAS DataBase Reference | 141-43-5(CAS DataBase Reference) |
NIST Chemistry Reference | Ethanolamine(141-43-5) |
EPA Substance Registry System | Ethanolamine (141-43-5) |
Safety Information
Hazard Codes | T,C |
Risk Statements | 20/21/22-34-39/23/24/25-23/24/25-10-52/53 |
Safety Statements | 26-36/37/39-45-61 |
RIDADR | UN 2924 3/PG 3 |
OEB | B |
OEL | TWA: 3 ppm (8 mg/m3), STEL: 6 ppm (15 mg/m3) |
WGK Germany | 1 |
RTECS | KJ5775000 |
F | 8-10-23 |
Autoignition Temperature | 410 °C |
TSCA | Yes |
HazardClass | 8 |
PackingGroup | III |
HS Code | 29221100 |
Hazardous Substances Data | 141-43-5(Hazardous Substances Data) |
Toxicity | LD50 orally in rats: 10.20 g/kg (Smyth) |
IDLA | 30 ppm |
Product Applications
Ethanolamine has a wide range of industrial applications. It is commonly employed as an absorption agent for removing carbon dioxide and hydrogen sulfide from natural gas and other gaseous streams. It is also used as a softening agent in leather processing and as a dispersing agent for agricultural chemicals. Other applications include its use in polishes, hair waving formulations, emulsifiers, and the manufacture of surface-active agents. In addition, ethanolamine is approved for use in materials intended for food production, processing, and packaging.
Chemically, ethanolamine exhibits reactions typical of both primary amines and alcohols. Two of its major industrial reactions involve combining with carbon dioxide or hydrogen sulfide to produce water-soluble salts, and reacting with long-chain fatty acids to form neutral ethanolamine soaps. These derivatives, particularly ethanolamine-based soaps, are widely used in cosmetic formulations as emulsifiers, thickeners, wetting agents, and detergents. Common applications include skin cleansers, creams, and lotions.
