Products Description
Propylene glycol methyl ether acetate (PGMEA), also known as propylene glycol monomethyl ether acetate or 1-methoxy-2-propyl acetate, has the molecular formula C₆H₁₂O₃. It is a colorless, hygroscopic liquid with a characteristic odor and is widely regarded as a versatile industrial solvent. Its molecular structure contains both ether and ester functional groups, incorporating polar and non-polar components that contribute to its excellent solvency and coupling properties. Consequently, PGMEA can dissolve a broad range of polar and non-polar substances, making it suitable for use in solvent-based coatings, screen-printing inks, paints, textile dyes, textile processing agents, and cleaning applications, including LCD manufacturing. It is a flammable liquid that may form explosive vapor–air mixtures at temperatures above its flash point of approximately 42°C.
PGMEA is commonly used as a high-performance solvent in industrial formulations because of its balanced polarity and effective dissolving capacity. It can be synthesized through the esterification of propylene glycol methyl ether with acetic acid in the presence of a solid acid catalyst. The resulting crude product is subsequently purified by distillation to obtain high-purity PGMEA.
Chemical Properties
Melting point | -87 °C |
Boiling point | 145-146 °C(lit.) |
density | 0.970 g/mL at 25 °C(lit.) |
vapor pressure | 3.7 mm Hg ( 20 °C) |
refractive index | n |
Fp | 110 °F |
storage temp. | Store below +30°C. |
solubility | water: soluble198g/L at 20°C |
form | Liquid |
color | Clear colorless |
PH | 4 (200g/l, H2O, 20℃) |
Odor | mild fruity odor |
Optical Rotation | -0.5827°(C=1.0041g/100ml CHCL3) |
explosive limit | 1.5%(V) |
Water Solubility | 19.8 g/L (25 ºC) |
BRN | 1751656 |
Henry's Law Constant | 2.9×100 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) |
Stability: | Stable. Flammable. Incompatible with strong oxidizing agents, acids, bases. |
Cosmetics Ingredients Functions | SOLVENT |
Cosmetic Ingredient Review (CIR) | 1-Methoxy-2-propyl acetate (108-65-6) |
InChI | 1S/C6H12O3/c1-5(4-8-3)9-6(2)7/h5H,4H2,1-3H3 |
InChIKey | LLHKCFNBLRBOGN-UHFFFAOYSA-N |
SMILES | COCC(C)OC(C)=O |
LogP | 1.2 at 20℃ |
CAS DataBase Reference | 108-65-6(CAS DataBase Reference) |
NIST Chemistry Reference | 1-Methoxy-2-propyl acetate(108-65-6) |
EPA Substance Registry System | 1-Methoxy-2-propyl acetate (108-65-6) |
Safety Information
Hazard Codes | T,Xi |
Risk Statements | 61-10-36 |
Safety Statements | 53-25-45 |
RIDADR | UN 3271 3/PG 3 |
WGK Germany | 3 |
RTECS | AI8925000 |
Autoignition Temperature | 669 °F |
TSCA | TSCA listed |
HazardClass | 3 |
PackingGroup | III |
HS Code | 29153990 |
Storage Class | 3 - Flammable liquids |
Hazard Classifications | Flam. Liq. 3 |
Hazardous Substances Data | 108-65-6(Hazardous Substances Data) |
Product Applications
1,2-Propanediolmonomethyletheracetateiswidelyusedasasolventinpaints,inks,lacquers,varnishes,cleaningproducts,andcoatingformulations.Itisalsoemployedincircuitboarddegreasingapplicationsandcertainfood-contactapplications.Additionally,itservesasasolventinphotoresistformulationsusedinthesemiconductorindustry.
