Product Overview
Hydroxylamine, with CAS number 7803-49-8, is an inorganic nitrogen-containing compound with the molecular formula H3NO and a molecular weight of 33.03 g/mol. It is also known as NH2OH and is widely used as a reducing agent and chemical intermediate in organic synthesis and industrial applications.
Hydroxylamine is a highly reactive substance that can participate in various chemical reactions involving carbonyl compounds and other functional groups. It is commonly used in the preparation of oximes, hydroxamic acids, and other nitrogen-containing derivatives. It also serves as an important reagent in laboratory research, chemical manufacturing, and material development.
Commercial products are frequently supplied as aqueous solutions, commonly at approximately 50% concentration. These solutions generally appear as clear, colorless to slightly yellow liquids. The exact concentration, purity, appearance, and physical properties depend on the supplier and product grade. Hydroxylamine solution is also used in polymer-related processes, analytical chemistry, and water treatment applications. Its strong reducing properties and chemical versatility make it a valuable raw material for specialized chemical production.
Safety and Storage
Hydroxylamine is a reactive chemical that requires careful handling, storage, and transportation. Depending on its concentration and formulation, it may present risks including harmful effects if swallowed, skin irritation, serious eye damage, allergic skin reactions, respiratory irritation, and environmental toxicity. Certain commercial formulations also carry additional hazard classifications. Always consult the current supplier-specific Safety Data Sheet (SDS) before handling or using the product.
Wear appropriate chemical-resistant gloves, protective clothing, and safety goggles or a face shield. Work in a well-ventilated area and avoid inhaling vapors or aerosols. Prevent direct contact with skin and eyes, and keep the product away from incompatible substances, particularly strong oxidizing agents and other materials identified in the SDS.
Store in a suitable, tightly closed, compatible container in a cool, well-ventilated area. Protect the material from excessive heat, direct sunlight, and contamination. Some commercial aqueous solutions require refrigerated storage, such as 2–10°C, while other formulations specify different temperature conditions. Follow the exact storage instructions provided by the manufacturer. Keep containers properly labeled and restrict access to trained personnel. Spills, residues, and empty containers should be handled according to applicable chemical waste regulations.
HYDROXYLAMINE Chemical Properties
Melting point | 7°C |
Boiling point | >100 °C |
density | 1.078 g/mL at 25 °C |
vapor pressure | 9 mm Hg ( 40 °C) |
refractive index | n20/D 1.393 |
RTECS | NC2975000 |
storage temp. | Store below +30°C. |
solubility | Water |
pka | pK (20°) 7.97 |
form | white flakes or needles |
color | white orthorhombic flakes or needles |
Water Solubility | Miscible with water, liquid ammonia and methanol. Slightly miscible with ether, benzene, carbon disulfide and chloroform. |
Merck | 13,4853 |
Stability: | Stable. Incompatible with oxidizing agents, potassium dichromate, chromium trioxide, zinc, calcium, copper, sodium, ammonia, carbonyls, phosphorus halides, pyridine, hypochlorites. |
InChIKey | AVXURJPOCDRRFD-UHFFFAOYSA-N |
CAS DataBase Reference | 7803-49-8(CAS DataBase Reference) |
NIST Chemistry Reference | Hydroxylamine(7803-49-8) |
EPA Substance Registry System | Hydroxylamine (7803-49-8) |
Safety Information
Hazard Codes | Xn,N |
Risk Statements | 5-22-37/38-41-43-48/22-50-40-21/22 |
Safety Statements | 23-26-36/37/39-47-61-22-46 |
RIDADR | UN 3082 9/PG 3 |
WGK Germany | 3 |
F | 4.8 |
TSCA | Yes |
HazardClass | 8 |
PackingGroup | II |
HS Code | 28251090 |
Hazardous Substances Data | 7803-49-8(Hazardous Substances Data) |
Toxicity | LD50 i.p. in mice: 1.83 mmol/kg (Smith, Layne) |
