2-Amino-3,5-Dibromopyrazine CAS#24241-18-7 Product Description
2-Amino-3,5-dibromopyrazine is a versatile brominated heterocyclic compound widely utilized as an important building block in organic synthesis, medicinal chemistry, and functional materials research. Its molecular structure features a pyrazine ring containing two nitrogen atoms, an amino group, and two bromine substituents. These structural characteristics provide multiple sites for further chemical modification, making it a valuable intermediate for the construction of more complex organic molecules.
In materials science, 2-Amino-3,5-dibromopyrazine can be employed in the synthesis of conjugated polymers designed for the detection of neurotoxins. The bromine substituents provide reactive sites for cross-coupling reactions, facilitating the introduction of conjugated molecular units and the development of functional polymeric materials with potential sensing applications.
In pharmaceutical research, this compound also serves as an important synthetic intermediate in the preparation of kinase inhibitors, particularly those targeting Rho-associated coiled-coil-containing protein kinases (ROCK). These applications highlight its significance in the development of biologically active compounds and advanced functional materials, making it a useful building block for both pharmaceutical synthesis and chemical research.
2-Amino-3,5-Dibromopyrazine CAS#24241-18-7 Chemical Properties
| Melting point | 114-117 °C (lit.) |
| Boiling point | 294.6±35.0 °C(Predicted) |
| Density | 2.287±0.06 g/cm3(Predicted) |
| Storage temp | Keep in dark place,Inert atmosphere,2-8°C |
| Solubility | soluble in Methanol |
| Pka | 0.81±0.10(Predicted) |
| Form | Powder |
| Color | Yellow to brown |
| InChIKey | DTLBKXRFWUERQN-UHFFFAOYSA-N |
| CAS DataBase Reference | 24241-18-7(CAS DataBase Reference) |
2-Amino-3,5-Dibromopyrazine CAS#24241-18-7 Safety Information
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-37/38-41 |
| Safety Statements | 26-36/39 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29339900 |
2-Amino-3,5-Dibromopyrazine CAS#24241-18-7 Product Application
2-Amino-3,5-dibromopyrazine is a versatile brominated pyrazine derivative used as an important building block in organic synthesis, pharmaceutical research, and functional materials development. It is utilized in the preparation of conjugated polymers designed for neurotoxin detection, serving as a precursor for the construction of functional polymeric structures with potential applications in chemical sensing. In addition, this compound acts as a key synthetic intermediate in the preparation of Rho-associated coiled-coil-containing protein kinase (ROCK) inhibitors. Owing to its reactive bromine substituents and amino-functionalized pyrazine ring, it provides opportunities for further molecular modification and the synthesis of structurally diverse compounds, making it valuable in medicinal chemistry and advanced materials research.
